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2-(2-Chloroethoxy)ethanol

Names

[ CAS No. ]:
628-89-7

[ Name ]:
2-(2-Chloroethoxy)ethanol

[Synonym ]:
Diglycol Ch
Ethanol, 2- (2-chloroethoxy)-
Ethanol, 2-(2-chloroethoxy)-
2-(2-chloroethoxy)-ethano
2-CHLOROETHOXYETHANOL
2-(2-Chloroethoxy)ethanol
2-(2-hydroxyethoxy)ethyl chloride
Diglycol chlorhydrin
chloroethoxyethanol
DEGCH
2-(2-chloroethoxy)-1-ethanol
EINECS 211-059-9
ethylene glycol mono-2-chloroethyl ether
2-(((9H-FLUOREN-9-YL)METHOXY)CARBONYL)-8-(BOC)-2,8-DIAZASPIRO[4.5]DECANE-3-CARBOXYLIC ACID
2-(2-chloroethoxy)-ethanol
MFCD00002870
2-(2-Cloroethoxy)Ethanol
Diglycolchlorohydrin

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
182.5±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C4H9ClO2

[ Molecular Weight ]:
124.566

[ Flash Point ]:
90.6±0.0 °C

[ Exact Mass ]:
124.029106

[ PSA ]:
29.46000

[ LogP ]:
-0.16

[ Vapour Pressure ]:
0.2±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.436

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
SOLUBLE

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KK1350000
CHEMICAL NAME :
Ethanol, 2-(2-chloroethoxy)-
CAS REGISTRY NUMBER :
628-89-7
BEILSTEIN REFERENCE NO. :
0506015
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C4-H9-Cl-O2
MOLECULAR WEIGHT :
124.58
WISWESSER LINE NOTATION :
QZO2G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
3 mL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S26-S36-S39

[ RIDADR ]:
UN 3334

[ WGK Germany ]:
2

[ RTECS ]:
KK1350000

[ HS Code ]:
2909499000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2909499000

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

GC method for quantitative determination of residual 2-(2-chloroethoxy) ethanol (CEE) and N-methyl-2-pyrrolidinone (NMP) in quetiapine.

Acta Pol. Pharm. 64(2) , 187-9, (2007)

Nitrophenyl-EGTA, a photolabile chelator that selectively binds Ca2+ with high affinity and releases it rapidly upon photolysis.

Proc. Natl. Acad. Sci. U. S. A. 91(1) , 187-91, (1994)

The synthesis and properties of a caged calcium are described. The compound is an ortho-nitrophenyl derivative of EGTA. It is synthesized in 10 steps and with 24% overall yield. The photosensitive che...

One-Pot Synthesis of Well-Defined Amphiphilic and Adaptative Block Copolymers via Versatile Combination of “Click” Chemistry and ATRP. Mespouille L, et al.

Macromol. Rapid Commun. 28(22) , 2151-58, (2007)


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