udp-alpha-d-galactose disodium salt

Names

[ Name ]:
udp-alpha-d-galactose disodium salt

[Synonym ]:
MFCD00077895
UDP-Gal UDP-galactose
UDP-α-D-GALACTOSE DISODIUM SALT
UDP-Gal

Biological Activity

[Description]:

UDP-Galactose disodium is a monosaccharide and a P2Y14 receptor agonist with an EC50 value of 0.67 μM. UDP-Galactose disodium is a substrate for the transferase beta-1, 4 galactosyltransferase V (B4GALT5)[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> P2Y Receptor

Research Areas >> Neurological Disease

[Target]

P2Y14 Receptor:0.67 μM (EC50)

[References]

[1]. Ko H, et al. Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J Med Chem. 2007 May 3;50(9):2030-9.

[2]. Drabavicius G, Daelemans D. Intermedilysin cytolytic activity depends on heparan sulfates and membrane composition. PLoS Genet. 2021 Feb 12;17(2):e1009387.

Chemical & Physical Properties

[ Density]:
1.97g/cm3

[ Molecular Formula ]:
C₁₅H₂₂N₂Na₂O₁₇P₂

[ Molecular Weight ]:
610.265

[ Flash Point ]:
27 °C

[ Exact Mass ]:
610.018921

[ PSA ]:
322.27000

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 50 mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
UN 2910 7

[ WGK Germany ]:
3

[ HS Code ]:
29400090

Articles

MUCILAGE-RELATED10 Produces Galactoglucomannan That Maintains Pectin and Cellulose Architecture in Arabidopsis Seed Mucilage.

Plant Physiol. 169 , 403-20, (2015)

Plants invest a lot of their resources into the production of an extracellular matrix built of polysaccharides. While the composition of the cell wall is relatively well characterized, the functions o...

Leishmania major UDP-sugar pyrophosphorylase salvages galactose for glycoconjugate biosynthesis.

Int. J. Parasitol. 45 , 783-90, (2015)

Leishmaniases are a set of tropical and sub-tropical diseases caused by protozoan parasites of the genus Leishmania whose severity ranges from self-healing cutaneous lesions to fatal visceral infectio...

Identification of a Highly Specific Isoflavone 7-O-glucosyltransferase in the soybean (Glycine max (L.) Merr.).

Plant Cell Physiol. 56 , 1512-20, (2015)

Isoflavone conjugates [7-O-β-D-glucosides and 7-O-(6″-malonyl-β-D-glucosides) of daidzein and genistein] accumulate in soybean roots and serve as the stored precursors of isoflavones (aglycons), which...

Related Compounds

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