Dnp-PYAYWMR (trifluoroacetate salt)

Names

[ Name ]:
Dnp-PYAYWMR (trifluoroacetate salt)

[Synonym ]:
L-Arginine, 1-(2,4-dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-, compd. with 2,2,2-trifluoroacetic acid (1:1)
Dnp-PYAYWMR (trifluoroacetate salt)
1-(2,4-Dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-L-arginine trifluoroacetate (1:1)

Biological Activity

[Description]:

Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

[Target]

MMP3[1]

[References]

[1]. Li Y, et al. Combination of serum matrix metalloproteinase-3 activity and EBV antibodies improves the diagnostic performance of nasopharyngeal carcinoma. J Cancer. 2020 Aug 18;11(20):6009-6018.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₆H₆₆F₃N₁₃O₁₆S

[ Molecular Weight ]:
1266.261

[ Exact Mass ]:
1265.442383

Related Compounds

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