135662-06-5

135662-06-5 structure

Name: Dnp-PYAYWMR (trifluoroacetate salt)
Chemical Name: Dnp-PYAYWMR (trifluoroacetate salt)
CAS Number: 135662-06-5
Molecular Formula: C₅₆H₆₆F₃N₁₃O₁₆S
Molecular Weight: 1266.261
Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
Create Date: 2021-06-16 20:24:00
Modify Date: 2025-08-25 09:00:20
Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].

Name	Dnp-PYAYWMR (trifluoroacetate salt)
Synonyms	L-Arginine, 1-(2,4-dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-, compd. with 2,2,2-trifluoroacetic acid (1:1) Dnp-PYAYWMR (trifluoroacetate salt) 1-(2,4-Dinitrophenyl)-L-prolyl-L-tyrosyl-L-alanyl-L-tyrosyl-L-tryptophyl-L-methionyl-L-arginine trifluoroacetate (1:1)

Description	Dnp-PYAYWMR is a peptide substrate that selectively targets MMP3. Dnp-PYAYWMR is cleaved by MMP3 to produce Dnp-PYA (nonfluorescent) and YWMR (fluorophore detectable at 360 nm). After incubation of MMP3 with Dnp-PYAYWMR for 2 h, MMP3 fluorescence intensity was measured. Ex/Em=328/350 nm[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
Target	MMP3[1]
References	[1]. Li Y, et al. Combination of serum matrix metalloproteinase-3 activity and EBV antibodies improves the diagnostic performance of nasopharyngeal carcinoma. J Cancer. 2020 Aug 18;11(20):6009-6018.