SAR7334
Names
[ CAS No. ]:
1333210-07-3
[ Name ]:
SAR7334
[Synonym ]:
Acetamide, 2-chloro-N-[3-[(1,1-dioxido-1,2-benzisothiazol-3-yl)amino]phenyl]-
2-Chloro-N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)amino]phenyl}acetamide
Biological Activity
[Description]:
SAR7334 is a potent TRPC6 (Transient receptor potential cation channel, subfamily C, member 6) inhibitor.
[Related Catalog]:
[In Vitro]
SAR7334 is a TRPC6 inhibitor, and used for treat the fibrotic disorders, such as focal segmental glomerulosclerosis, skeletal muscle dysfunction[1].
[References]
[Related Small Molecules]
capsaicin
|
Capsazepine
|
EIPA
|
Diphenyleneiodonium chloride
|
HC-030031
|
SKF-96365
|
HC 067047
|
AMG 9810
|
GSK-1016790A
|
PF-4840154
|
RN-1734
|
SAR 7334
|
AMG-517
|
SB-366791
|
IcilinAG-3-5
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Molecular Formula ]:
C21H22ClN3O
[ Molecular Weight ]:
367.87
[ Exact Mass ]:
349.028778
[ LogP ]:
2.13
[ Index of Refraction ]:
1.697