LY2940094

Names

[ CAS No. ]:
1307245-86-8

[ Name ]:
LY2940094

Biological Activity

[Description]:

LY2940094 is a potent, selective and orally available nociceptin receptor (NOP) antagonist with an Ki of 0.105 nM.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

Research Areas >> Neurological Disease

[Target]

Ki: 0.105 nM (NOP)[1]

[References]

[1]. Rorick-Kehn LM, et al. A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models. Alcohol Clin Exp Res. 2016 May;40(5):945-54.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃ClF₂N₄O₂S

[ Molecular Weight ]:
480.96

[ Storage condition ]:
2-8℃

Related Compounds

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