N(4), O(2')-dimethylcytidine

Names

[ Name ]:
N(4), O(2')-dimethylcytidine

[Synonym ]:
N,2'-O-Dimethylcytidine
Cytidine,N-methyl-2'-O-methyl
N4,O2'-Dimethylcytidin
N4,2'-O-dimethylcytidine
N4-Methyl-2'-O-methyl-cytidin
N4,O2'-dimethyl-cytidine

Biological Activity

[Description]:

N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.54g/cm3

[ Boiling Point ]:
475.4ºC at 760mmHg

[ Melting Point ]:
203-205 °C

[ Molecular Formula ]:
C₁₁H₁₇N₃O₅

[ Molecular Weight ]:
271.27

[ Flash Point ]:
241.3ºC

[ Exact Mass ]:
271.11700

[ PSA ]:
109.33000

[ Vapour Pressure ]:
4.91E-11mmHg at 25°C

[ Index of Refraction ]:
1.636

Safety Information

[ Hazard Codes ]:
Xn

N(4), O(2')-dimethylcytidine

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds