N-palmitoylserinol

Names

[ Name ]:
N-palmitoylserinol

[Synonym ]:
N-(1,3-Dihydroxy-2-propanyl)hexadecanamide
Hexadecanamide, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-
N-palmitoylserinol
Palmitoyl Serinol
N-palmitoyl serinol

Biological Activity

[Description]:

Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin[1][2].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Cannabinoid Receptor

[In Vitro]

Palmitoyl serinol (N-Palmitoyl serinol) stimulates ceramide production through a CB1-dependent mechanism in in vitro model of skin inflammation[2].

[References]

[1]. Shin KO, et al. N-Palmitoyl Serinol Stimulates Ceramide Production through a CB1-Dependent Mechanism in In Vitro Model of Skin Inflammation. Int J Mol Sci. 2021;22(15):8302. Published 2021 Aug 2.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
525.9±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₉H₃₉NO₃

[ Molecular Weight ]:
329.518

[ Flash Point ]:
271.9±27.3 °C

[ Exact Mass ]:
329.292999

[ PSA ]:
69.56000

[ LogP ]:
5.68

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.475

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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