N-palmitoylserinol

Modify Date: 2024-01-03 11:13:22

N-palmitoylserinol Structure
N-palmitoylserinol structure
Common Name N-palmitoylserinol
CAS Number 126127-31-9 Molecular Weight 329.518
Density 1.0±0.1 g/cm3 Boiling Point 525.9±40.0 °C at 760 mmHg
Molecular Formula C19H39NO3 Melting Point N/A
MSDS N/A Flash Point 271.9±27.3 °C

 Use of N-palmitoylserinol


Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin[1][2].

 Names

Name N-(1,3-dihydroxypropan-2-yl)hexadecanamide
Synonym More Synonyms

 N-palmitoylserinol Biological Activity

Description Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin[1][2].
Related Catalog
In Vitro Palmitoyl serinol (N-Palmitoyl serinol) stimulates ceramide production through a CB1-dependent mechanism in in vitro model of skin inflammation[2].
References

[1]. Shin KO, et al. N-Palmitoyl Serinol Stimulates Ceramide Production through a CB1-Dependent Mechanism in In Vitro Model of Skin Inflammation. Int J Mol Sci. 2021;22(15):8302. Published 2021 Aug 2.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 525.9±40.0 °C at 760 mmHg
Molecular Formula C19H39NO3
Molecular Weight 329.518
Flash Point 271.9±27.3 °C
Exact Mass 329.292999
PSA 69.56000
LogP 5.68
Vapour Pressure 0.0±3.1 mmHg at 25°C
Index of Refraction 1.475

 Synthetic Route

~88%

N-palmitoylserinol Structure

N-palmitoylserinol

CAS#:126127-31-9

Literature: Jupally, Vijay Reddy; Kota, Rajesh; Dornshuld, Eric Van; Mattern, Daniell L.; Tschumper, Gregory S.; Jiang, De-En; Dass, Amala Journal of the American Chemical Society, 2011 , vol. 133, # 50 p. 20258 - 20266

~%

N-palmitoylserinol Structure

N-palmitoylserinol

CAS#:126127-31-9

Literature: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM; HADASIT MEDICAL RESEARCH SERVICES and DEVELOPMENT LTD. Patent: WO2009/60457 A1, 2009 ; Location in patent: Page/Page column 43-44 ;

 Precursor & DownStream

Precursor  3

DownStream  0

 Synonyms

N-(1,3-Dihydroxy-2-propanyl)hexadecanamide
Hexadecanamide, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-
N-palmitoylserinol
Palmitoyl Serinol
N-palmitoyl serinol