nTZDpa

Names

[ Name ]:
nTZDpa

[Synonym ]:
nTzDpa
NZA

Biological Activity

[Description]:

nTZDpa is an antibiotic. nTZDpa is a PPARG partial agonist. nTZDpa has antibacterial activity. nTZDpa is effective against growing and persistent Staphylococcus aureus by lipid bilayer disruption[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Kim W, et al. Discovery and Optimization of nTZDpa as an Antibiotic Effective Against Bacterial Persisters. ACS Infect Dis. 2018 Nov 9;4(11):1540-1545.

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
628.9ºC at 760mmHg

[ Molecular Formula ]:
C₂₂H₁₅Cl₂NO₂S

[ Molecular Weight ]:
428.33

[ Flash Point ]:
334.2ºC

[ Exact Mass ]:
427.02000

[ PSA ]:
67.53000

[ LogP ]:
6.84580

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.672

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

Related Compounds

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