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(+)-PHENSERINE

Names

[ CAS No. ]:
116839-68-0

[ Name ]:
(+)-PHENSERINE

[Synonym ]:
(+)-PHENSERINE

Biological Activity

[Description]:

(+)-Phenserine is a novel selective cholinesterase noncompetitive inhibitor with an IC50 of 45.3 μM.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> AChE
Research Areas >> Neurological Disease
Research Areas >> Endocrinology

[Target]

IC50: 45.3 μM (AChE), Ki: 48 μM (AChE).


[References]

[1]. al-Jafari AA, et al. Kinetics of human erythrocyte acetylcholinesterase inhibition by a novel derivative of physostigmine: phenserine. Biochem Biophys Res Commun. 1998 Jul 9; 248(1):180-5.


[Related Small Molecules]

Galantamine | Choline glycerophosphate | benzethonium chloride | Malathion | (-)-Huperzine A | pyridostigmine bromide | Scopoletin | Tacrine hydrochloride hydrate | Huperzine A | Epiberberine chloride | Protriptyline hydrochloride | Imperatorin | Itopride hydrochloride | Enzacamene | Corydaline

Chemical & Physical Properties

[ Molecular Formula ]:
C20H23N3O2

[ Molecular Weight ]:
337.41600

[ Exact Mass ]:
337.17900

[ PSA ]:
48.30000

[ LogP ]:
3.68310

Related Compounds

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