SCUTELLAREIN TETRAMETHYL ETHER

Names

[ Name ]:
SCUTELLAREIN TETRAMETHYL ETHER

[Synonym ]:
MFCD00017442
4',5,6,7-Tetramethoxyflavone
Tetramethylscutellarein
5,6,7,4'-scutellarein tetramethylether
Scutellarein tetramethyl ether
5,6,7-trimethoxy-2-(4-methoxyphenyl)chromen-4-one
Tetramethyl-O-scutellarin
Flavone,4',5,6,7-tetramethoxy
Tetra-O-methylscutellarein

Biological Activity

[Description]:

Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is a bioactive component of Siam weed extract. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) exhibits anti-inflammatory activity through NF-κB pathway[1]. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) modulats of bacterial drug resistance via efflux pump inhibition[2]. Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) can enhance blood coagulation[3].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Pandith H, et al. Effect of Siam weed extract and its bioactive component scutellarein tetramethyl ether on anti-inflammatory activity through NF-κB pathway. J Ethnopharmacol. 2013 May 20;147(2):434-41.

[2]. Maia GL, et al. Flavonoids from Praxelis clematidea R.M. King and Robinson modulate bacterial drug resistance. Molecules. 2011 Jun 10;16(6):4828-35.

[3]. Triratana T, et al. Effect of Eupatorium odoratum on blood coagulation. J Med Assoc Thai. 1991 May;74(5):283-7.

Chemical & Physical Properties

[ Density]:
1.243g/cm3

[ Boiling Point ]:
525.7ºC at 760mmHg

[ Melting Point ]:
142-143ºC

[ Molecular Formula ]:
C₁₉H₁₈O₆

[ Molecular Weight ]:
342.34300

[ Flash Point ]:
232.4ºC

[ Exact Mass ]:
342.11000

[ PSA ]:
67.13000

[ LogP ]:
3.49440

[ Vapour Pressure ]:
3.84E-11mmHg at 25°C

[ Index of Refraction ]:
1.574

Safety Information

[ Safety Phrases ]:
S22

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%