Gardenin B

Names

[ Name ]:
Gardenin B

[Synonym ]:
5-Hydroxy-4',6,7,8-tetramethoxyflavone
Demethyltangeretin
4H-1-Benzopyran-4-one, 5-hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)-
5-O-demethyltangeretin
Gardenin B
5-Hydroxy-2-(4-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
5-demethyltangeretin
5-Hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
5-hydroxy-6,7,8,4'-tetramethoxyflavone
5-O-Desmethyltangeretin
5-Hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
6,7,8,4'-tetramethoxy-5-hydroxyflavone
5-hydroxy-6,7,8-trimethoxy-2-(4-methoxyphenyl)chromen-4-one
5-hydroxy-4',6,7,8-tetramethoxy-flavone

Biological Activity

[Description]:

Gardenin B is a flavonoid isolated from Baccharis scandens. Gardenin B induces cell death in human leukemia cells involves multiple caspases[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Cabrera J, et al. Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species. Chem Biol Interact. 2016 Aug 25;256:220-7.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
582.0±50.0 °C at 760 mmHg

[ Melting Point ]:
180-181ºC

[ Molecular Formula ]:
C₁₉H₁₈O₇

[ Molecular Weight ]:
358.342

[ Flash Point ]:
210.8±23.6 °C

[ Exact Mass ]:
358.105255

[ PSA ]:
87.36000

[ LogP ]:
2.27

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.593

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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