4-Methoxybenzaldehyde

Names

[ CAS No. ]:
123-11-5

[ Name ]:
4-Methoxybenzaldehyde

[Synonym ]:
Obepin
4-Methoxybenzald
Anisaldehyd
FEMA 2670
AUBEPINE
Anisal
4-Methoxybenzaldehyde
4-methoxy-benzaldehyde
MFCD00003385
p-Anisaldehyde,contains Acetic Acid,H2SO4) Ethanol
p-Anisaldehyde
EINECS 204-602-6
ANISALDEHYDE

Biological Activity

[Description]:

4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound that is soluble in acetone. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking [1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Showler AT , et al. Effects of the Botanical Compound p-Anisaldehyde on Horn Fly (Diptera: Muscidae) Repellency, Mortality, and Reproduction. J Med Entomol. 2018 Jan 10;55(1):183-192.

Chemical & Physical Properties

[ Density]:
1.121

[ Boiling Point ]:
248-249 ºC

[ Melting Point ]:
-1 °C

[ Molecular Formula ]:
C₈H₈O₂

[ Molecular Weight ]:
136.148

[ Flash Point ]:
116 ºC

[ Exact Mass ]:
136.052429

[ PSA ]:
26.30000

[ LogP ]:
1.70

[ Vapour density ]:
4.7 (vs air)

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.571-1.574

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ2625000

CHEMICAL NAME :: p-Anisaldehyde

CAS REGISTRY NUMBER :: 123-11-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C8-H8-O2

MOLECULAR WEIGHT :: 136.16

WISWESSER LINE NOTATION :: VHR DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1510 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1859 mg/kg

TOXIC EFFECTS :: Gastrointestinal - necrotic changes Gastrointestinal - other changes Liver - fatty liver degeneration

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1260 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 55200 ug/kg/30D-I

TOXIC EFFECTS :: Cardiac - changes in heart weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in other cell count (unspecified)

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 3560 umol/L

REFERENCE :: MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5044 No. of Facilities: 6993 (estimated) No. of Industries: 40 No. of Occupations: 62 No. of Employees: 100333 (estimated) No. of Female Employees: 61328 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S26-S36-S45-S36/37-S16-S7

[ RIDADR ]:
UN 3316 9/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
BZ2625000

[ Packaging Group ]:
I; II; III

[ HS Code ]:
29124900

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2912499000

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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