6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone

Names

[ Name ]:
6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone

[Synonym ]:
.6'-hydroxy-3,4,2',3',4'-pentamethoxy-trans()-chalcone
2'-hydroxy-3,4,4',5',6'-pentamethoxychalcone
.6'-Hydroxy-3,4,2',3',4'-pentamethoxy-trans()-chalkon

Biological Activity

[Description]:

2'-Hydroxy-3,4,4',6'-tetramethoxychalcone (Compound 5) has antibacterial activity, with a MIC value of 10 μg/mL for E. coli and S. epidermis. 2'-Hydroxy-3,4,4',6'-tetramethoxychalcone can be isolated from Piper obliquum[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Valdivia C, et al. Bioactive alkenylphenols from Piper obliquum. Bioorg Med Chem. 2008 Apr 1;16(7):4120-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₂O₇

[ Molecular Weight ]:
374.38

[ Exact Mass ]:
374.13700

[ PSA ]:
83.45000

[ LogP ]:
3.33130

6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream