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2-(3,4-dihydroxyphenyl)-5,6,7-trihydroxychromen-4-one

Names

[ CAS No. ]:
18003-33-3

[ Name ]:
2-(3,4-dihydroxyphenyl)-5,6,7-trihydroxychromen-4-one

[Synonym ]:
6-Hydroxyluteolin
Demethylpedalitin
6-hydroxylutelin
3',4',5,6,7-Pentahydroxyflavone
2-(3,4-dihydroxyphenyl)-5,6,7-trihydroxychromen-4-one
5,6,7,3',4'-pentahydroxyflavone
6-OH-Luteolin

Biological Activity

[Description]:

6-Hydroxyluteolin (Compound 17) is a flavonoid compound. 6-Hydroxyluteolin has an inhibitory effect on aldose reductase (AR) [1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Metabolic Enzyme/Protease >> Aldose Reductase

[References]

[1]. Mercader AG, et al. QSAR prediction of inhibition of aldose reductase for flavonoids. Bioorg Med Chem. 2008. 16(15):7470-6.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H10O7

[ Molecular Weight ]:
302.23600

[ Exact Mass ]:
302.04300

[ PSA ]:
131.36000

[ LogP ]:
1.98800

Safety Information

[ Hazard Codes ]:
Xn

[ HS Code ]:
2914501900

Synthetic Route

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%