N-Acetyl-DL-methionine
Names
[ CAS No. ]:
1115-47-5
[ Name ]:
N-Acetyl-DL-methionine
[Synonym ]:
Methionine, N-acetyl-, DL-
2-(acetylamino)-4-(methylthio)butanoic acid
2-acetamido-4-methylsulfanylbutanoic acid
2-Acetamido-4-(methylthio)butanoic acid
N-acetyl-methionine
DL-Methionine, N-acetyl-
Methionine, N-acetyl-
ACETYL-DL-METHIONINE
N-Acetylmethionine
UNII:383941IGXN
Methionamine
MFCD00008681
Ac-DL-Met-OH
DL-N-Acetylmethionine
EINECS 214-224-3
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
453.6±40.0 °C at 760 mmHg
[ Melting Point ]:
117-119 °C(lit.)
[ Molecular Formula ]:
C7H13NO3S
[ Molecular Weight ]:
191.248
[ Flash Point ]:
228.1±27.3 °C
[ Exact Mass ]:
191.061615
[ PSA ]:
91.70000
[ LogP ]:
-0.19
[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C
[ Index of Refraction ]:
1.511
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- PD0500000
- CHEMICAL NAME :
- Methionine, N-acetyl-, DL-
- CAS REGISTRY NUMBER :
- 1115-47-5
- BEILSTEIN REFERENCE NO. :
- 1725554
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H13-N-O3-S
- MOLECULAR WEIGHT :
- 191.27
- WISWESSER LINE NOTATION :
- 1VMYVQ2S1 -DL
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 91,163,1952
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
PD0500000
[ HS Code ]:
2930909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2930909090
[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Anal. Biochem. 308 , 285-293, (2002)
The hydrolysis of N-acetyl-L-methionine, N-acetylglycine, N-acetyl-L-phenylalanine, and N-acetyl-L-alanine at 298.35K by porcine kidney acylase I (EC 3.5.1.14) was monitored by the heat released upon ...
Model sclerotization studies. 4. Generation of N-acetylmethionyl catechol adducts during tyrosinase-catalyzed oxidation of catechols in the presence of N-acetylmethionine.Arch. Insect Biochem. Physiol. 38(1) , 44-52, (1998)
Incubation of catechol with mushroom tyrosinase in the presence of N-acetylmethionine resulted in the generation of an adduct. This product was identified to be N-acetylmethionyl catechol, on the basi...
Identification of N-acetylmethionine as the product released during the NH2-terminal processing of a pseudo-class I actin.J. Biol. Chem. 264(19) , 11491-6, (1989)
Genes for the various isoactins define two classes of actin. Class I actin genes code for Met-Asp(Glu)-actin, and class II actin genes code for Met-X-Asp(Glu)-actin where X is usually cysteine. Amino ...