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Epimedin C

Names

[ CAS No. ]:
110642-44-9

[ Name ]:
Epimedin C

[Synonym ]:
4H-1-Benzopyran-4-one, 3-[[6-deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-mannopyranosyl]oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
Epmedin C
3-{[6-Deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-mannopyranosyl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-7-yl β-D-glucopyranoside
4H-1-Benzopyran-4-one, 3-((6-deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-mannopyranosyl)oxy)-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
N1912
X1133
Epimedin C
3-{[6-Deoxy-2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-mannopyranosyl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4-oxo-4H-chromen-7-yl β-D-glucopyranoside

Biological Activity

[Description]:

Epmedin C, a natural product, has estrogen-like effects for ovariectomized mice.IC50 value:Target:In vitro:In vivo: Anesthetized with 0.4%pentobarbital sodium, mice of the ovariectomized group were conducted with Bilateral oophorectomy, while fat beside ovaries were removed on mice of the sham-operation group. Compared with the sham-operation group, body weight of mice of model group were significantly increased, uterus weight and uterine factor and estradiol levels were significantly reduced, which suggested a significant difference. In comparison of the ovariectomized group, body weight of mice were relieved significantly and uterus weight and uterine factor and estradiol levels were increased significantly in all Epmedin C groups [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Natural Products >> Flavonoids
Research Areas >> Others

[References]

[1]. WEN Yu, et al. Effect of Epmedin C on Estrogen in Ovariectomized Mice. Modern Chinese Medicine, 2012-05


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Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
1062.1±65.0 °C at 760 mmHg

[ Melting Point ]:
147 °C(dec.)

[ Molecular Formula ]:
C39H50O19

[ Molecular Weight ]:
822.803

[ Flash Point ]:
322.2±27.8 °C

[ Exact Mass ]:
822.294617

[ PSA ]:
297.12000

[ LogP ]:
3.19

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.678

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds