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Epimedin B

Names

[ CAS No. ]:
110623-73-9

[ Name ]:
Epimedin B

[Synonym ]:
Epmedin B
4H-1-Benzopyran-4-one, 3-[(6-deoxy-2-O-β-D-xylopyranosyl-α-L-mannopyranosyl)oxy]-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-
3-{[6-Deoxy-2-O-(β-D-xylopyranosyl)-α-L-mannopyranosyl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4-oxo-4H-chromen-7-yl β-D-glucopyranoside
3-{[6-Deoxy-2-O-(β-D-xylopyranosyl)-α-L-mannopyranosyl]oxy}-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-en-1-yl)-4-oxo-4H-chromen-7-yl β-D-glucopyranoside
EpimedinB
4H-1-Benzopyran-4-one, 3-((6-deoxy-2-O-β-D-xylopyranosyl-α-L-mannopyranosyl)oxy)-7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
Epimedin B

Biological Activity

[Description]:

Epimedin B, a component extracted from Epimedii Folium, is reported to have antiosteoporotic activity.IC50 value:Target:In vitro:In vivo: Prednisolone-induced osteoporosis model using zebrafish was used to evaluate the antiosteoporotic activity of micro amount epimedin B. The result showed that 1 μmol·L- 1epimedin B groups were significantly increased when compared with model group; Epimedin B can prevent zebrafish osteoporosis induced by prednisolone [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Natural Products >> Flavonoids
Research Areas >> Others

[References]

[1]. ZHAN Yang, et al. Evaluation of Antiosteoporotic Activity for Micro Amount Icariin and Epimedin B Based on the Osteoporosis Model Using Zebrafish. Chinese Pharmaceutical Journal, 2014-01

[2]. Cui L, et al. Metabolite profiles of epimedin B in rats by ultraperformance liquid chromatography/quadrupole-time-of-flight mass spectrometry. J Agric Food Chem. 2013 Apr 17;61(15):3589-99.

[3]. ZHANG Hua-feng, et al. Effects of microwave radiation on extraction of epimedin B from Epimedii Folium. Chinese Traditional and Herbal Drugs, 2011-09


[Related Small Molecules]

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Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
1066.1±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C38H48O19

[ Molecular Weight ]:
808.776

[ Flash Point ]:
325.6±27.8 °C

[ Exact Mass ]:
808.278992

[ PSA ]:
297.12000

[ LogP ]:
2.87

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.685

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds