PD 120697

Names

[ Name ]:
PD 120697

Biological Activity

[Description]:

PD 120697 is an orally active dopamine (DA) agonist. PD 120697 inhibits striatal DA synthesis, DA neuronal firing, spontaneous locomotor activity, and reverses Reserpine (HY-N0480)-induced depression[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

[References]

[1]. Jaen JC, et al. 4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties. J Med Chem. 1990 Jan;33(1):311-7.

Chemical & Physical Properties

[ Density]:
1.182g/cm3

[ Boiling Point ]:
383.6ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅N₃S

[ Molecular Weight ]:
221.32200

[ Flash Point ]:
185.8ºC

[ Exact Mass ]:
221.09900

[ PSA ]:
71.12000

[ LogP ]:
1.86840

[ Vapour Pressure ]:
4.34E-06mmHg at 25°C

[ Index of Refraction ]:
1.612