108351-91-3

108351-91-3 structure

Name: PD 120697
Chemical Name: 4-(1-prop-2-enyl-3,6-dihydro-2H-pyridin-5-yl)-1,3-thiazol-2-amine
CAS Number: 108351-91-3
Molecular Formula: C₁₁H₁₅N₃S
Molecular Weight: 221.32200
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2016-03-02 16:08:58
Modify Date: 2024-01-15 14:43:48
PD 120697 is an orally active dopamine (DA) agonist. PD 120697 inhibits striatal DA synthesis, DA neuronal firing, spontaneous locomotor activity, and reverses Reserpine (HY-N0480)-induced depression[1].

Name	4-(1-prop-2-enyl-3,6-dihydro-2H-pyridin-5-yl)-1,3-thiazol-2-amine

Description	PD 120697 is an orally active dopamine (DA) agonist. PD 120697 inhibits striatal DA synthesis, DA neuronal firing, spontaneous locomotor activity, and reverses Reserpine (HY-N0480)-induced depression[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
References	[1]. Jaen JC, et al. 4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties. J Med Chem. 1990 Jan;33(1):311-7.