Betaine
Names
[ CAS No. ]:
107-43-7
[ Name ]:
Betaine
[Synonym ]:
(Carboxymethyl)trimethylammonium inner salt Oxyneurine
2-N,N,N-trimethylammonio acetate
rubrinec
MFCD00012123
EINECS 203-490-6
OXYNEURINE
(Carboxymethyl)trimethylammonium inner salt
Additive Screening
jortaine
BET
Betain
trimethylammonioacetate
Aminocoat
(Carboxymethyl)trimethylammonium inner salt,Oxyneurine
Betaine
Abromine
LYCINE
wolfberry Extract
trimethylglycine
Chemical & Physical Properties
[ Density]:
1.00 g/mL at 20 °C
[ Melting Point ]:
301-305 °C (dec.)
[ Molecular Formula ]:
C5H11NO2
[ Molecular Weight ]:
117.146
[ Exact Mass ]:
117.078979
[ PSA ]:
40.13000
[ LogP ]:
-3.25
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable. Hygroscopic. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
160 g/100 mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DS5900000
- CHEMICAL NAME :
- Betaine
- CAS REGISTRY NUMBER :
- 107-43-7
- BEILSTEIN REFERENCE NO. :
- 3537113
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C5-H11-N-O2
- MOLECULAR WEIGHT :
- 117.17
- WISWESSER LINE NOTATION :
- QV1K1&1&1 &Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10800 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 3,28,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 830 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 16,529,1967
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DS5900000
[ HS Code ]:
2923900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2923900090
[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Mol. Cell Biochem. 400(1-2) , 9-15, (2015)
Recently, we showed that the fused chorismate-utilizing enzyme from the antibiotic-producing soil bacterium Streptomyces venezuelae is an anthranilate synthase (designated SvAS), not a 2-amino-2-deoxy...
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease.Br. J. Pharmacol. 171(17) , 4073-86, (2014)
Overactive lipolysis in adipose tissue contributes to the pathogenesis of alcoholic liver disease (ALD); however, the mechanisms involved have not been elucidated. We previously reported that chronic ...
Generation and characterization of a murine model of Bietti crystalline dystrophy.Invest. Ophthalmol. Vis. Sci. 55(9) , 5572-81, (2014)
Bietti crystalline dystrophy (BCD) is a rare, autosomal recessive, progressive, degenerative eye disease caused by mutations in the CYP4V2 gene, for which no treatments are currently available. Cyp4v3...