Ethyl cinnamate
Names
[ CAS No. ]:
103-36-6
[ Name ]:
Ethyl cinnamate
[Synonym ]:
TRANS-ETHYLCINNAMATE
Cinnamic Acid Ethyl Ester
RARECHEM AL BI 0143
Ethylcinnamat
Ethyl cinnamate
Ethyl (2E)-3-phenyl-2-propenoate
Ethylphenylacryate
ethyl 3-phenyl-2-propenoate
Ethyl trans-3-Phenylacrylate
Ethyl ciamate
FEMA 2430
2-Propenoic acid, 3-phenyl-, ethyl ester, (2E)-
ethyl 3-phenylacrylate
Ethyl (2E)-3-phenylacrylate
trans-3-Phenylacrylic Acid Ethyl Ester
EINECS 203-104-6
ETHYL TRANS-CINNAMATE
Zimtsaeureethylester
2-Propenoic acid, 3-phenyl-, ethyl ester, (E)-
Ethyl Gui
ethyl (2E)-3-phenylprop-2-enoate
Ethyl Cinnamate Trans
MFCD00009189
ethyl dihydrocinnamate
3-phenylacrylic acid ethyl ester
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
269.4±9.0 °C at 760 mmHg
[ Melting Point ]:
6-8 °C(lit.)
[ Molecular Formula ]:
C11H12O2
[ Molecular Weight ]:
176.212
[ Flash Point ]:
148.6±9.9 °C
[ Exact Mass ]:
176.083725
[ PSA ]:
26.30000
[ LogP ]:
2.71
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.550
[ Storage condition ]:
Refrigerator (+4°C)
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, acids, bases, reducing agents. Combustible.
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GD9010000
- CHEMICAL NAME :
- Cinnamic acid, ethyl ester
- CAS REGISTRY NUMBER :
- 103-36-6
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C11-H12-O2
- MOLECULAR WEIGHT :
- 176.23
- WISWESSER LINE NOTATION :
- 2OV1U1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952- Volume(issue)/page/year: 33(5),48,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952- Volume(issue)/page/year: 33(5),48,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 12,719,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952- Volume(issue)/page/year: 33(5),48,1974 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 9520 mg/kg/17W-I
- TOXIC EFFECTS :
- Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes
- REFERENCE :
- VPITAR Voprosy Pitaniya. Problems of Nutrition. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-10, 1932-41; V.11- 1952- Volume(issue)/page/year: 33(5),48,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5185 No. of Facilities: 541 (estimated) No. of Industries: 5 No. of Occupations: 16 No. of Employees: 11257 (estimated) No. of Female Employees: 2716 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
T+
[ Risk Phrases ]:
R20
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
GD9010000
[ HS Code ]:
2916399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916399090
[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Molecules 20 , 10980-1016, (2015)
Developed from crosses between Vitis vinifera and North American Vitis species, interspecific hybrid grape varieties are becoming economically significant in northern areas, where they are now extensi...
Novel natural product-based cinnamates and their thio and thiono analogs as potent inhibitors of cell adhesion molecules on human endothelial cells.Eur. J. Med. Chem. 46 , 5498-511, (2011)
In the present study, we report the design and synthesis of novel analogs of cinnamates, thiocinnamates and thionocinnamates and evaluated the potencies of these analogs to inhibit TNF-α induced ICAM-...
[Effects of allelochemicals ethyl cinnamate on the growth and physiological characteristics of Chlorella pyrenoidosa].Huan Jing Ke Xue 34(1) , 156-62, (2013)
The effects of ethyl cinnamate on the growth and physiological characteristics of Chlorella pyrenoidosa were studied. The allelopathic mechanisms were explored, from views of chlorophyll a content, an...