Ethyl 3-phenyl-2-oxiranecarboxylate
Names
[ CAS No. ]:
121-39-1
[ Name ]:
Ethyl 3-phenyl-2-oxiranecarboxylate
[Synonym ]:
ethyl3-phenyloxirane
ETHYL PHENYLGLYCIDATE FCC
FEMA 2454
3-phenyl-glycidicaciethylester
rac-3-phenyloxirane-2-carboxylic acid ethyl ester
trans-ethyl 2-phenylglycidate
ethyl 3-phenyl oxirane-2-carboxylate
3-phenyloxirane-2-carboxylic acid ethyl ester
MFCD00005123
Ethyl 3-Phenylglycidate
ethyl phenylglycidate
cis-ethyl-3-phenyloxirane-2-carboxylate
ETHYL A B-EPOXYHYDROCINNAMATE
3-Phenylglycidic Acid Ethyl Ester
ethyl3-phenyloxirane-2
ethyl3-phenyloxiranecarboxylate
ethyl 3-phenyl-2-oxiranecarboxylate
EINECS 204-467-3
Ethyl 3-Phenyloxiranecarboxylate
ethyl2,3-epoxy-3-phenylpropion
Chemical & Physical Properties
[ Density]:
1.102 g/mL at 25 °C(lit.)
[ Boiling Point ]:
96 °C0.5 mm Hg(lit.)
[ Molecular Formula ]:
C11H12O3
[ Molecular Weight ]:
192.21100
[ Flash Point ]:
>230 °F
[ Exact Mass ]:
192.07900
[ PSA ]:
38.83000
[ LogP ]:
1.68960
[ Vapour Pressure ]:
0.00184mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.518(lit.)
[ Storage condition ]:
0-6°C
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MB4970000
- CHEMICAL NAME :
- Glycidic acid, 3-phenyl-, ethyl ester
- CAS REGISTRY NUMBER :
- 121-39-1
- BEILSTEIN REFERENCE NO. :
- 0163394
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C11-H12-O3
- MOLECULAR WEIGHT :
- 192.23
- WISWESSER LINE NOTATION :
- T3OTJ BOV2 CR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 103 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 138,1,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4609 No. of Facilities: 18 (estimated) No. of Industries: 1 No. of Occupations: 13 No. of Employees: 3245 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4609 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 1557 (estimated) No. of Female Employees: 276 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
MB4970000
[ HS Code ]:
2918990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918990090
[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
Articles
Biotechnol. Lett. 25(24) , 2113-6, (2003)
A Pseudomonas sp. was isolated with enantioselective epoxide hydrolase activity to ethyl 3-phenylglycidate. Cells grown on sucrose and suspended in 10% (v/v) dimethyl formamide as co-solvent produced ...
Investigation of the mutagenicity of ethylphenylglycidate.Mutat. Res. 138(1) , 1-8, (1984)
EPG and an in vitro digest of EPG by pepsin and pancreatin simulating mammalian digestion have been examined for genotoxicity in 4 mutagenicity tests employing different genetic endpoints. In the Salm...