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8-Azidoadenosine-5'-diphosphate Sodium Salt

Names

[ CAS No. ]:
102185-14-8

[ Name ]:
8-Azidoadenosine-5'-diphosphate Sodium Salt

[Synonym ]:
8-N3-ADP SODIUM SALT
8-Azidoadenosine-5'-diphosphate Sodium Salt

Biological Activity

[Description]:

8-Azido-ADP (disodium) is a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. 8-Azido-ADP (disodium) causes irreversible inhibition of adenine nucleotide exchange in a light-dependent reaction. 8-Azido-ADP (disodium) inhibits the normal state 4 → 3 transitions of mitochondrial respiration induced by ADP[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Research Areas >> Others

[Target]

Adenine nucleotide[1]


[References]

[1]. SchHafer G, et al. 8-azido-ADP, a covalent-binding inhibitor of mitochondrial adenine nucleotide translocation. FEBS Lett. 1976 Apr 15;64(1):185-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H13N8NaO10P2

[ Molecular Weight ]:
490.19500

[ Exact Mass ]:
490.01300

[ PSA ]:
279.77000

Related Compounds