Vitamin E
Names
[ CAS No. ]:
10191-41-0
[ Name ]:
Vitamin E
[Synonym ]:
(2R)-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
DL-TOCOPHEROL
dl-alpha-Tocopherol(E)
ecyl)
ephanyl
alpha-Tocopherol
(±)-α-Tocopherol
(2R)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]chroman-6-ol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-, (2R)-
vitamin
A-TOCOPHEROL
Irganox E 201
(2R)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-trimethyltridecyl]-6-chromanol
MFCD00072051
DL-VITAMIN E
dl-Alpha-Tocopherol
EINECS 233-466-0
DL-α-Tocopherol
(+/-)-alpha-Tocopherol,synthetic
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
485.9±0.0 °C at 760 mmHg
[ Melting Point ]:
2-4°C
[ Molecular Formula ]:
C29H50O2
[ Molecular Weight ]:
430.706
[ Flash Point ]:
210.2±24.4 °C
[ Exact Mass ]:
430.381073
[ PSA ]:
29.46000
[ LogP ]:
11.90
[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C
[ Index of Refraction ]:
1.495
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GA8746000
- CHEMICAL NAME :
- 6-Chromanol, 2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-
- CAS REGISTRY NUMBER :
- 10191-41-0
- BEILSTEIN REFERENCE NO. :
- 0094012
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C29-H50-O2
- MOLECULAR WEIGHT :
- 430.79
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 2500 ug/kg
- REFERENCE :
- CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 25,163,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1133 No. of Facilities: 104 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 555 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1133 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 114 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301 + H311 + H331-H370
[ Precautionary Statements ]:
P210-P260-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
GA8746000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Pharm. Dev. Technol. 20(2) , 169-75, (2015)
The main objective of the present study was to develop formulations of noscapine hydrochloride hydrate with enhanced solubility and bioavailability using co-solvent- and cyclodextrin-based approaches....
Development of novel formulations to enhance in vivo transdermal permeation of tocopherol.Acta. Pharm. 64(3) , 299-309, (2014)
Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical ...
Coffee silverskin: a possible valuable cosmetic ingredient.Pharm. Biol. 53(3) , 386-94, (2015)
Currently, there is a great tendency in cosmetic area to use natural extracts. Coffee silverskin (CS) is the most abundant solid by-product generated during roasting of coffee processing.To evaluate d...