Alkaline hydrolysis of tertiary N-(2-pyridyl) carbamates. Contradictory evidence between nucleophilic and general base catalysis

D Silva, F Norberto, S Santos, P Hervés

Index: Silva, Daniel; Norberto, Fatima; Santos, Susana; Herves, Pablo Journal of Physical Organic Chemistry, 2009 , vol. 22, # 3 p. 221 - 228

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Abstract

Abstract The mechanism of the alkaline hydrolysis of phenyl N-methyl-N-(2-pyridyl) carbamate was investigated in order to evaluate the type of catalysis involved. The kinetic solvent isotope effect, the α-effect for the hydrolysis in peroxymonocarbonate ion, the

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