A Highly Versatile Catalyst System for the Cross??Coupling of Aryl Chlorides and Amines
…, A Sappong??Kumankumah…
Index: Lundgren, Rylan J.; Sappong-Kumankumah, Antonia; Stradiotto, Mark Chemistry - A European Journal, 2010 , vol. 16, # 6 p. 1983 - 1991
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Citation Number: 118
Abstract
Abstract The syntheses of 2-(di-tert-butylphosphino)-N, N-dimethylaniline (L1, 71%) and 2- (di-1-adamantylphosphino)-N, N-dimethylaniline (L2, 74%), and their application in Buchwald–Hartwig amination, are reported. In combination with [Pd (allyl) Cl] 2 or [Pd (cinnamyl) Cl] 2, these structurally simple and air-stable P, N ligands enable the cross- coupling of aryl and heteroaryl chlorides, including those bearing as substituents ...
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