Synthesis and antitumor activity of 20 (S)-camptothecin derivatives: carbamate-linked, water-soluble derivatives of 7-ethyl-10-hydroxycamptothecin.

沢田誠吾， 岡島悟， 相山律男， 野方健一郎…

Index: Chemical and Pharmaceutical Bulletin, , vol. 39, # 6 p. 1446 - 1454

Full Text: HTML

Citation Number: 282

Abstract

... systems" and CPT-ll is now under phase II of clinical trials in Japan.” Chemistry We reported ... at the Japanese—United States Congress of Pharmaceutical Sciences, 1987, Honolulu, Hawaii, Dec ... the 14th International Congress of Chemother., 5) 6) 7) 8) 9) 10) 11) 12) 13) 14) Vol. ...

Related Articles:

Synthesis and antitumor activity of 20 (S)-camptothecin derivatives: A-ring modified and 7, 10-disubstituted camptothecins.

[Chemical and Pharmaceutical Bulletin, , vol. 39, # 12 p. 3183 - 3188]

Scalable Synthetic Route to 2-Amino-5-hydroxypropiophenone: Efficient Formal Synthesis of Irinotecan

[Rao, A. V. Rama; Rao, Ramakrishna; Yadav; Khagga, Mukkanti Synthetic Communications, 2013 , vol. 43, # 12 p. 1661 - 1667]

Different hydrolases involved in bioactivation of prodrug-type angiotensin receptor blockers: carboxymethylenebutenolidase and carboxylesterase 1

[Drug Metabolism and Disposition, , vol. 41, # 11 p. 1888 - 1895]

A General Synthetic Approach to the (20S)??Camptothecin Family of Antitumor Agents by a Regiocontrolled Cascade Radical Cyclization of Aryl Isonitriles

[Josien, Hubert; Ko, Sung-Bo; Bom, David; Curran, Dennis P. Chemistry - A European Journal, 1998 , vol. 4, # 1 p. 67 - 83]

Synthetic Studies on Camptothecins. Part 3

[Kuang, Yun-Yan; Niu, Jing-Ze; Chen, Fen-Er Helvetica Chimica Acta, 2010 , vol. 93, # 10 p. 2094 - 2099]

More Articles...