Carbenes from vilsmeier reagents by the action of bases in POCl 3; the umpolung of vilsmeier reagents
Y Cheng, S Goon, O Meth-Cohn
Index: Cheng, Ying; Goon, Simon; Meth-Cohn, Otto Chemical Communications, 1996 , # 11 p. 1395 - 1396
Full Text: HTML
Citation Number: 0
Abstract
When para-substituted N-methylformanilides are treated in POCl3 with a base, the corresponding Vilsmeier reagent formed undergoes ready deprotonation to give an aminochlorocarbene from which a range of products derive; a carba-moyl chloride, N- methylisatins, dimers [1, 2-dichloro-1, 2-bis (N-methyl-N-arylamino) ethenes], trimers {5, 10- dimethyl-11-(N-methyl-N-arylamino)-10H-indolo [3, 2-b] quinolinium and 5, 10-dimethyl- ...
Related Articles:
[Puerto Galvis, Carlos E.; Kouznetsov, Vladimir V. Organic and Biomolecular Chemistry, 2013 , vol. 11, # 42 p. 7372 - 7386]
Synthesis of novel 5-substituted indirubins as protein kinases inhibitors
[Beauchard, Anne; Ferandin, Yoan; Frere, Stephane; Lozach, Olivier; Blairvacq, Melina; Meijer, Laurent; Thiery, Valerie; Besson, Thierry Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 18 p. 6434 - 6443]
[Kumar, Chebolu Naga Sesha Sai Pavan; Devi, Chebrolu Lavanya; Rao, Vaidya Jayathirtha; Palaniappan, Srinivasan Synlett, 2008 , # 13 p. 2023 - 2027]
[Li, Jian; Liu, Yuejin; Li, Chunju; Jia, Xueshun Chemistry - A European Journal, 2011 , vol. 17, # 27 p. 7409 - 7413]
[Puerto Galvis, Carlos E.; Kouznetsov, Vladimir V. Organic and Biomolecular Chemistry, 2013 , vol. 11, # 42 p. 7372 - 7386]