Design, Synthesis, and Evaluation of Su-gar Amino Acid Based Inhibitors of Pro-tein Prenyl Transferases PFT and PGGT-1
…, GA van der Marel, M Overhand
Index: Green, Graham; Griffith, William P.; Hollinshead, David M.; Ley, Steven V.; Schroeder, Martin Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 681 - 686
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Citation Number: 19
Abstract
... Journal of Medicinal Chemistry. ... Scheme 3. Synthesis 1−8, 11, and 13 a. a Reagents and conditions: (i) (a) MeOH/1,4-dioxane/4 M NaOH; (b) RP-HPLC purification; (ii) (a) Pd/C, H 2 , EtOH/CHCl 3 (100%); (b) TFA/DCM 1/1 v/v, iPr 3 SiH; (c) Fmoc-Cys(StBu)-OH, BOP, N ...
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