Synthesis of Indoles via Palladium [0]-Mediated Ullmann Cross-Coupling of o-Halonitroarenes with α-Halo-enones or-enals
MG Banwell, BD Kelly, OJ Kokas, DW Lupton
Index: Banwell, Martin G.; Kelly, Brian D.; Kokas, Okanya J.; Lupton, David W. Organic Letters, 2003 , vol. 5, # 14 p. 2497 - 2500
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Citation Number: 100
Abstract
Palladium [0]-mediated Ullmann cross-coupling of o-halonitrobenzene (1) and various related nitroarenes with a range of α-halo-enones (eg, 2) or-enals readily affords the expected α-arylenones, eg, 3, or-enals, which are converted into the corresponding indoles, eg, 4, on reaction with dihydrogen in the presence of Pd on C.
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