ZIKV-IN-2
Modify Date: 2024-04-06 00:18:17
ZIKV-IN-2 structure
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Common Name | ZIKV-IN-2 | ||
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| CAS Number | 910582-16-0 | Molecular Weight | 574.75 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C39H42O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ZIKV-IN-2ZIKV-IN-2 (compound 3a) is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 38.86 μM. ZIKV-IN-2 inhibits ZIKV replication and infection. ZIKV-IN-2 can be used in research of Zika virus (ZIKV)[1]. |
| Name | ZIKV-IN-2 |
|---|
| Description | ZIKV-IN-2 (compound 3a) is a potent ZIKV NS5 methyl transferase (MTase) inhibitor with an IC50 value of 38.86 μM. ZIKV-IN-2 inhibits ZIKV replication and infection. ZIKV-IN-2 can be used in research of Zika virus (ZIKV)[1]. |
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| Related Catalog | |
| Target |
IC50: 38.86 μM (MTase)[1] |
| In Vitro | ZIKV-IN-2 (compound 3a; 0.08-50 μM) inhibits the expression of ZIKV E protein with an EC50 value of 6.17 μM and inhibits ZIKV replication and infection[1]. ZIKV-IN-2 (0.08-50 μM; 96 h) has low cytotoxicity in Vero, Huh7 and A549 cells[1]. Cell Viability Assay[1] Cell Line: Vero, Huh7 and A549 cells Concentration: 0.08, 0.4, 2, 10, and 50 μM Incubation Time: 96 hours Result: Exhibited low cytotoxicities to Vero cells, Huh7 cells and A549 cells with CC50>200 μM to all three cell lines. |
| References |
| Molecular Formula | C39H42O4 |
|---|---|
| Molecular Weight | 574.75 |