Fmoc-NH-PEG4-alcohol

Modify Date: 2024-01-10 15:07:14

Fmoc-NH-PEG4-alcohol Structure
Fmoc-NH-PEG4-alcohol structure
Common Name Fmoc-NH-PEG4-alcohol
CAS Number 868594-41-6 Molecular Weight 415.48
Density N/A Boiling Point N/A
Molecular Formula C23H29NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-NH-PEG4-alcohol


Fmoc-NH-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Fmoc-NH-PEG4-alcohol

 Fmoc-NH-PEG4-alcohol Biological Activity

Description Fmoc-NH-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C23H29NO6
Molecular Weight 415.48