MMP13-IN-4

Modify Date: 2024-01-27 22:15:04

MMP13-IN-4 Structure
MMP13-IN-4 structure
 Common Name MMP13-IN-4
CAS Number 514855-02-8 Molecular Weight 485.29
Density N/A Boiling Point N/A
Molecular Formula C21H17BrN4O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMP13-IN-4


MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM)，involved in osteoarthritis (OA)[1].

 Names

Name MMP13-IN-4

 MMP13-IN-4 Biological Activity

Description MMP13-IN-4 (compound 13) is a potent and selective inhibitor of MMP-13 (IC50=14.6 μM)，involved in osteoarthritis (OA)[1].
Related Catalog
Target

IC50: 91 μM (MMP-1), 99 μM (MMP-2), 68 μM (MMP-9), 14.6 μM (MMP-13), 63 μM (MMP-14)[1]

References

[1]. Cuffaro D, et al. Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization. Int J Mol Sci. 2023 Jul 4;24(13):11098.  

 Chemical & Physical Properties

Molecular Formula C21H17BrN4O5
Molecular Weight 485.29
InChIKey RITQIXDLUYCXJN-ZMOGYAJESA-N
SMILES CC(=NNC(=O)Cc1ccc([N+](=O)[O-])cc1)c1ccc(NC(=O)c2ccc(Br)o2)cc1
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Chemsrc provides MMP13-IN-4(CAS#:514855-02-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of MMP13-IN-4 are included as well.>> amp version: MMP13-IN-4

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