AChE/BChE-IN-9
Modify Date: 2025-08-24 23:47:39
AChE/BChE-IN-9 structure
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Common Name | AChE/BChE-IN-9 | ||
|---|---|---|---|---|
| CAS Number | 2761542-55-4 | Molecular Weight | 365.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H19N3O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AChE/BChE-IN-9AChE/BChE-IN-9 (Compound 7a) is a potent, orally active AChE and BChE inhibitor with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. AChE/BChE-IN-9 is also an efficacious antioxidant with an IC50 of 57.35 μM. AChE/BChE-IN-9 is able to chelate iron and modulates aggregation of amyloid β1-42. AChE-IN-16 can cross the BBB[1]. |
| Name | AChE/BChE-IN-9 |
|---|
| Description | AChE/BChE-IN-9 (Compound 7a) is a potent, orally active AChE and BChE inhibitor with IC50 values of 5.74 μM and 14.05 μM against hAChE and eqBChE, respectively. AChE/BChE-IN-9 is also an efficacious antioxidant with an IC50 of 57.35 μM. AChE/BChE-IN-9 is able to chelate iron and modulates aggregation of amyloid β1-42. AChE-IN-16 can cross the BBB[1]. |
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| Related Catalog | |
| Target |
IC50: 5.74 μM (AChE), 14.05 μM (BChE)[1] |
| In Vivo | AChE/BChE-IN-9 (Compound 7a) (0-25 mg/kg) improves spatial memory in cognitive deficit mice[1]. |
| References |
| Molecular Formula | C20H19N3O4 |
|---|---|
| Molecular Weight | 365.38 |
| InChIKey | XVKHPTDTSZLRHX-XVNBXDOJSA-N |
| SMILES | COc1cc(C=CC(=O)NCC(=O)Nc2ccc3[nH]ccc3c2)ccc1O |