PDGFRα/FLT3-ITD-IN-3

Modify Date: 2024-02-13 19:25:46

PDGFRα/FLT3-ITD-IN-3 structure	Common Name	PDGFRα/FLT3-ITD-IN-3
	CAS Number	2761259-22-5	Molecular Weight	477.65
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₉N₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PDGFRα/FLT3-ITD-IN-3

PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].

Name	PDGFRα/FLT3-ITD-IN-3

Description	PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα/FLT3 with IC50s of 0.153 and 0.004 μM, respectively. PDGFRα/FLT3-ITD-IN-3 has the potential for the research of acute myeloid leukemia or chronic eosinophilic leukemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3
References	[1]. Vlková K, et al. Synthesis and biological activity evaluation of novel 2,6,9-trisubstituted purine conjugates as potential protein kinases inhibitors. Bioorg Med Chem Lett. 2022 Mar 15;60:128603

Molecular Formula	C₂₆H₃₉N₉
Molecular Weight	477.65

PDGFRα/FLT3-ITD-IN-3

Use of PDGFRα/FLT3-ITD-IN-3

Names

PDGFRα/FLT3-ITD-IN-3 Biological Activity

Chemical & Physical Properties