COX-1/2-IN-3

Modify Date: 2023-05-16 21:39:47

COX-1/2-IN-3 structure	Common Name	COX-1/2-IN-3
	CAS Number	2428387-82-8	Molecular Weight	332.22
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₈N₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of COX-1/2-IN-3

COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity[1].

Name	COX-1/2-IN-3

Description	COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-1 COX-2
In Vivo	COX-1/2-IN-3 (Compound 7a) (1.25 and 0.625 mg/ear) exhibits a high level of in vivo anti-inflammatory activity, reducing ear edema and myeloperoxidase (MPO) activity[1].
References	[1]. Gonçalves DS, et al. Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity. Bioorg Med Chem. 2020 Jun 15;28(12):115549.

Molecular Formula	C₁₄H₈N₂O₈
Molecular Weight	332.22