NBI-6024

Modify Date: 2024-04-06 08:13:39

NBI-6024 structure	Common Name	NBI-6024
	CAS Number	239480-61-6	Molecular Weight	1521.72
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₆H₁₁₂N₂₀O₂₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of NBI-6024

NBI-6024, an altered peptide ligand (APL), is an epitope recognized by inflammatory interferon-gamma-producing T helper lymphocytes in type 1 diabetic patients[1][2].

Name	NBI-6024

Description	NBI-6024, an altered peptide ligand (APL), is an epitope recognized by inflammatory interferon-gamma-producing T helper lymphocytes in type 1 diabetic patients[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	NBI-6024 (0.005-20 mg/kg, s.c.) delays the onset and reduces the incidence of diabetes in mice[2]. Animal Model: Nonobese diabetic (NOD) mice[2] Dosage: 0.005, 0.05, 0.5, 5, 10, 20 mg/kg Administration: Subcutaneous injection (s.c.) Result: Observed dose-dependent induction of responsiveness to the immunizing antigen at 5, 10, 20 mg/kg (tested by culturing spleen cells pooled from mice).

Molecular Formula	C₆₆H₁₁₂N₂₀O₂₁
Molecular Weight	1521.72