239480-61-6
239480-61-6 structure
- Name: NBI-6024
- Chemical Name: NBI-6024
- CAS Number: 239480-61-6
- Molecular Formula: C66H112N20O21
- Molecular Weight: 1521.72
- Catalog: Research Areas Metabolic Disease
- Create Date: 2022-11-21 23:36:38
- Modify Date: 2024-04-06 08:13:39
-
NBI-6024, an altered peptide ligand (APL), is an epitope recognized by inflammatory interferon-gamma-producing T helper lymphocytes in type 1 diabetic patients[1][2].
| Name | NBI-6024 |
|---|
| Description | NBI-6024, an altered peptide ligand (APL), is an epitope recognized by inflammatory interferon-gamma-producing T helper lymphocytes in type 1 diabetic patients[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | NBI-6024 (0.005-20 mg/kg, s.c.) delays the onset and reduces the incidence of diabetes in mice[2]. Animal Model: Nonobese diabetic (NOD) mice[2] Dosage: 0.005, 0.05, 0.5, 5, 10, 20 mg/kg Administration: Subcutaneous injection (s.c.) Result: Observed dose-dependent induction of responsiveness to the immunizing antigen at 5, 10, 20 mg/kg (tested by culturing spleen cells pooled from mice). |
| Molecular Formula | C66H112N20O21 |
|---|---|
| Molecular Weight | 1521.72 |