Sotuletinib dihydrochloride
Modify Date: 2024-01-04 12:26:22
Sotuletinib dihydrochloride structure
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Common Name | Sotuletinib dihydrochloride | ||
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| CAS Number | 2222138-40-9 | Molecular Weight | 471.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24Cl2N4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Sotuletinib dihydrochlorideSotuletinib (BLZ945) dihydrochloride is an orally active and blood-brain barrier-permeable CSF1-R-specific inhibitor (IC50=1 nM). Sotuletinib (BLZ945) dihydrochloride induces tumor cell apoptosis and effectively inhibits tumor growth in mouse models. Sotuletinib dihydrochloride can be used in cancer and amyotrophic lateral sclerosis (ALS) research[1]. |
| Name | Sotuletinib dihydrochloride |
|---|
| Description | Sotuletinib (BLZ945) dihydrochloride is an orally active and blood-brain barrier-permeable CSF1-R-specific inhibitor (IC50=1 nM). Sotuletinib (BLZ945) dihydrochloride induces tumor cell apoptosis and effectively inhibits tumor growth in mouse models. Sotuletinib dihydrochloride can be used in cancer and amyotrophic lateral sclerosis (ALS) research[1]. |
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| Related Catalog | |
| Target |
IC50: CSF1-R (1 nM)[1]. |
| References |
| Molecular Formula | C20H24Cl2N4O3S |
|---|---|
| Molecular Weight | 471.40 |