JMI-346

Modify Date: 2025-08-25 13:41:20

JMI-346 Structure
JMI-346 structure
 Common Name JMI-346
CAS Number 2091841-46-0 Molecular Weight 336.39
Density N/A Boiling Point N/A
Molecular Formula C19H20N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JMI-346


JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent[1].

 Names

Name JMI-346

 JMI-346 Biological Activity

Description JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQS (3D7; IC50=13 µM) and CQR (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent[1].
Related Catalog
References

[1]. Uddin A, et al. Identification and structure-activity relationship (SAR) studies of carvacrol derivatives as potential anti-malarial against Plasmodium falciparum falcipain-2 protease. Bioorg Chem. 2020 Oct;103:104142.

 Chemical & Physical Properties

Molecular Formula C19H20N4O2
Molecular Weight 336.39
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Chemsrc provides JMI-346(CAS#:2091841-46-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of JMI-346 are included as well.>> amp version: JMI-346

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