Pyrazine-d4

Modify Date: 2024-01-18 22:23:10

Pyrazine-d4 Structure
Pyrazine-d4 structure
Common Name Pyrazine-d4
CAS Number 1758-62-9 Molecular Weight 84.11260
Density 1.108g/cm3 Boiling Point 116ºC(lit.)
Molecular Formula C4D4N2 Melting Point 55-57ºC(lit.)
MSDS Chinese USA Flash Point 132 °F
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

 Use of Pyrazine-d4


Pyrazine-d4 is the deuterium labeled Pyrazine[1].

 Names

Name 2,3,5,6-tetradeuteriopyrazine
Synonym More Synonyms

 Pyrazine-d4 Biological Activity

Description Pyrazine-d4 is the deuterium labeled Pyrazine[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

 Chemical & Physical Properties

Density 1.108g/cm3
Boiling Point 116ºC(lit.)
Melting Point 55-57ºC(lit.)
Molecular Formula C4D4N2
Molecular Weight 84.11260
Flash Point 132 °F
Exact Mass 84.06260
PSA 25.78000
LogP 0.47660
Vapour Pressure 19.7mmHg at 25°C
Index of Refraction 1.503
Storage condition 2-8°C

 Safety Information

Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger
Hazard Statements H228-H315-H319-H335
Precautionary Statements P210-P261-P305 + P351 + P338
RIDADR UN 1325 4.1/PG 3
WGK Germany 3

 Synthetic Route

~%

Pyrazine-d4 Structure

Pyrazine-d4

CAS#:1758-62-9

Literature: Hieida, Toshikazu; Maehara, Masayoshi; Nibu, Yoshinori; Shimada, Hiroko; Shimada, Ryoichi Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 3 p. 925 - 927

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

Pyrazine-d4
Deuterated pyrazine
tetradeuterio-pyrazine
pyrazole-d4
MFCD00075192