Pyrazine-d4

Names

[ CAS No. ]:
1758-62-9

[ Name ]:
Pyrazine-d4

[Synonym ]:
Pyrazine-d4
Deuterated pyrazine
tetradeuterio-pyrazine
pyrazole-d4
MFCD00075192

Biological Activity

[Description]:

Pyrazine-d4 is the deuterium labeled Pyrazine[1].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.108g/cm3

[ Boiling Point ]:
116ºC(lit.)

[ Melting Point ]:
55-57ºC(lit.)

[ Molecular Formula ]:
C4D4N2

[ Molecular Weight ]:
84.11260

[ Flash Point ]:
132 °F

[ Exact Mass ]:
84.06260

[ PSA ]:
25.78000

[ LogP ]:
0.47660

[ Vapour Pressure ]:
19.7mmHg at 25°C

[ Index of Refraction ]:
1.503

[ Storage condition ]:
2-8°C

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H228-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P305 + P351 + P338

[ RIDADR ]:
UN 1325 4.1/PG 3

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds