Antitumor agent-63
Modify Date: 2025-08-25 20:49:15
Antitumor agent-63 structure
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Common Name | Antitumor agent-63 | ||
|---|---|---|---|---|
| CAS Number | 1627600-90-1 | Molecular Weight | 846.79 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C38H46N4O18 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Antitumor agent-63Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1]. |
| Name | Antitumor agent-63 |
|---|
| Description | Antitumor agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, is an antitumor agent without toxicity towards normal cells. Antitumor agent-63 shows high stability and very weak direct topoisomerase I (Topo I) inhibition[1]. |
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| Related Catalog | |
| Target |
Top1 |
| In Vitro | Antitumor agent-63 (Compound 40) shows cytotoxicity activities with IC50 values of 1.2, 0.8, 30.5 and >100 µM against HepG2, HCT-116, SW1990 and HEK-293, respectively[1]. |
| References |
| Molecular Formula | C38H46N4O18 |
|---|---|
| Molecular Weight | 846.79 |
| InChIKey | YFRBFEVHTILPOU-MLGQGFJNSA-N |
| SMILES | CCC1(OC(=O)NCCOCCOC2OC(CO)C(O)C(O)C2OC2OC(CO)C(O)C(OC(N)=O)C2O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 |