Tau-aggregation-IN-1

Modify Date: 2025-08-26 11:20:53

Tau-aggregation-IN-1 structure	Common Name	Tau-aggregation-IN-1
	CAS Number	1619269-19-0	Molecular Weight	507.69
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₇N₅O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tau-aggregation-IN-1

Tau-aggregation-IN-1 (Compound D-519) is a tau441 protein aggregation inhibitor with an IC50 of 21 µM. Tau-aggregation-IN-1 is also a dopamine D2 and D3 receptor agonist[1].

Name	Tau-aggregation-IN-1

Description	Tau-aggregation-IN-1 (Compound D-519) is a tau441 protein aggregation inhibitor with an IC50 of 21 µM. Tau-aggregation-IN-1 is also a dopamine D2 and D3 receptor agonist[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
Target	D2 Receptor D3 Receptor
References	[1]. Iva Ziu, et al. The multifunctional dopamine D2/D3 receptor agonists also possess inhibitory activity against the full-length tau441 protein aggregation. Bioorg Med Chem. 2020 Sep 15;28(18):115667.

Molecular Formula	C₂₈H₃₇N₅O₂S
Molecular Weight	507.69

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