Metallo-β-lactamase-IN-8
Modify Date: 2025-11-24 20:14:42
Metallo-β-lactamase-IN-8 structure
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Common Name | Metallo-β-lactamase-IN-8 | ||
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| CAS Number | 1610537-25-1 | Molecular Weight | 326.76 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H11ClN2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Metallo-β-lactamase-IN-8Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1]. |
| Name | Metallo-β-lactamase-IN-8 |
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| Description | Metallo-β-lactamase-IN-8 (compound 17) is a potent, reversible and competitive broad-spectrum inhibitor of metallo-β-lactamases (MβLs), with IC50s of 1.3 μM, 5.7 μM, 9.8 μM, and 9.9 μM for L1, ImiS, IMP-1 and VIM-2, respectively. Metallo-β-lactamase-IN-8 exhibits antibacterial activity[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C13H11ClN2O4S |
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| Molecular Weight | 326.76 |
| InChIKey | RPRDFXZWOJZMRF-UHFFFAOYSA-N |
| SMILES | O=C(NO)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 |