β-Lactamase-IN-7

Modify Date: 2024-01-10 08:01:00

β-Lactamase-IN-7 Structure
β-Lactamase-IN-7 structure
Common Name β-Lactamase-IN-7
CAS Number 2419903-21-0 Molecular Weight 313.44
Density N/A Boiling Point N/A
Molecular Formula C16H15N3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of β-Lactamase-IN-7


β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae[1].

 Names

Name β-Lactamase-IN-7

 β-Lactamase-IN-7 Biological Activity

Description β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae[1].
Related Catalog
Target

Ki: 1.26 μM (VIM-1), 0.54 μM (VIM-4)[1]

References

[1]. Legru A, et al. 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. Eur J Med Chem. 2021;226:113873.

 Chemical & Physical Properties

Molecular Formula C16H15N3S2
Molecular Weight 313.44