Plm IV inhibitor-1

Modify Date: 2025-08-28 00:20:29

Plm IV inhibitor-1 Structure
Plm IV inhibitor-1 structure
Common Name Plm IV inhibitor-1
CAS Number 1539276-41-9 Molecular Weight 613.83
Density N/A Boiling Point N/A
Molecular Formula C37H51N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Plm IV inhibitor-1


Plm IV inhibitor-1 (compound 6) is a potent plasmepsin IV (Plm IV) inhibitor with IC50s of 4.1, 0.80, 0.25, 0.35 µM for Plm I, Plm II, Plm IV, Cat D, respectively[1].

 Names

Name Plm IV inhibitor-1

 Plm IV inhibitor-1 Biological Activity

Description Plm IV inhibitor-1 (compound 6) is a potent plasmepsin IV (Plm IV) inhibitor with IC50s of 4.1, 0.80, 0.25, 0.35 µM for Plm I, Plm II, Plm IV, Cat D, respectively[1].
Related Catalog
Target

IC50: 4.1 µM (Plm I); 0.80 µM (Plm II); 0.25 µM (Plm IV); 0.35 µM (Cat D)[1]

References

[1]. Jaudzems K, et al. Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit. ACS Med Chem Lett. 2014 Jan 13;5(4):373-7.

 Chemical & Physical Properties

Molecular Formula C37H51N5O3
Molecular Weight 613.83
InChIKey CSWMOEBFXLXGOK-JHOUSYSJSA-N
SMILES CCCN(CCC)C(=O)c1cc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)(C)c2ccccn2)cc(N2CCCCC2)c1
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