Shanghai Nianxing Industrial Co., Ltd
China
Product Name: JAK3 covalent inhibitor-1
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Purity: 98.0%
Stocking Period: 10 Day
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2300106-50-5

2300106-50-5 structure

2300106-50-5 structure

Name: JAK3 covalent inhibitor-1
Chemical Name: JAK3 covalent inhibitor-1
CAS Number: 2300106-50-5
Molecular Formula: C₂₂H₁₇FN₆O₂S
Molecular Weight: 448.47
Catalog: Signaling Pathways Epigenetics JAK
Create Date: 2019-06-29 15:28:05
Modify Date: 2025-08-25 12:31:40
JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1].

Name	JAK3 covalent inhibitor-1

Description	JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1].
Related Catalog	Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Research Areas >> Inflammation/Immunology
Target	JAK3:11 nM (IC50)
References	[1]. Casimiro-Garcia A, et al. Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors. J Med Chem. 2018 Dec 13;61(23):10665-10699.

Molecular Formula	C₂₂H₁₇FN₆O₂S
Molecular Weight	448.47

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